Midazolam in Refractory Neonatal Seizures

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Midazolam for treatment of refractory neonatal seizures. A case report.

Midazolam is a short-acting water soluble benzodiazepine that has been used with an increasing frequency in the last years. Although there are reports on its use in status epilepticus, there is none in the neonatal period. A pre-term (35 w) AGA newborn infant with a severe hypoxic-ischemic encephalopathy secondary to grade III hyaline membrane disease developed status epilepticus in the first 6...

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Intranasal Midazolam for Seizures

Seizures in children are a frightening experience for families and care providers. Because the duration of seizure activity impacts on morbidity and mortality, effective methods for seizure control should be instituted as soon as possible, preferably before arrival at the hospital. Since parental methods of drug delivery are not available to most caregivers, and rectal diazepam, the most common...

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Neonatal seizures

The incidence of seizures in infants born at term is 0.53 per 1000 live births; the incidence is even higher in preterm infants, ranging from 113% of very low birthweight infants3. Variations of described numbers of incidence can be explained by different diagnostic definitions and methods used. Most of these epidemiological studies include only clinical seizures. The exact incidence of elect...

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Neonatal seizures.

In childhood, the risk for seizures is greatest in the neonatal period. Currently used therapies have limited efficacy. Although the treatment of neonatal seizures has not significantly changed in the past several decades, there has been substantial progress in understanding developmental mechanisms that influence seizure generation and responsiveness to anticonvulsants. This review includes an...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2005

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-19-3-5